Based on the scientific consensus, leading plastic pollution, environmental and public health experts and advocates across the globe have joined together to issue a Declaration of Concern and Call to Action. Across the U.S., Europe, Asia, Latin America and Africa 165 signatories, representing a variety of voices are calling for a more precautionary approach to regulating chemicals used in food packaging and seeking action not only to eliminate plastics, but all forms of single-use packaging due to the human health risks they pose. The UNWRAPPED Project Partners are leading regional education and advocacy initiatives to reduce human health risks associated with food packaging.